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Infrared, Red & Blue Light: Peer-Reviewed Research

Last Updated: October 2026. This page is a reading list of published, peer-reviewed studies on red, blue, and infrared light, with links to the original papers. Each description says what the study looked at; please see the papers themselves for the researchers' findings. These studies were carried out by independent researchers using their own equipment, including laboratory setups and clinical lasers. They did not test Starlite Smile devices and are not claims about our products.

Showing 10 studies

Near-infrared and red LED light on gum cells — laboratory study

Infrared

A laboratory cell study from the University of Pennsylvania School of Dental Medicine looking at how human gum cells respond to near-infrared and red LED light.

· Journal of Dental Research

Light wavelengths in photobiomodulation — literature review

Infrared

A review of published research drawn from PubMed, Scopus, and Web of Science, comparing how red, infrared, blue, and violet light have been studied.

· International Journal of Molecular Sciences

High-intensity red LED light in a gum research model

Red light

Research from Osaka Dental University looking at high-intensity red LED light in a gum (gingival) research model.

· Scientific Reports

630 nm red light — cell and animal study

Red light

A laboratory study looking at 630 nm red light in cell cultures and mice, including gene activity related to collagen.

· Lasers in Medical Science

Red LED face mask (630 nm) — study of 20 volunteers

Red light

A study in which 20 volunteers used a red LED face mask for three months. It looked at facial skin, not the mouth.

· Skin Research and Technology

405 nm blue LED light and oral biofilm — laboratory study

Blue light

Laboratory research from Tokyo Medical and Dental University looking at 405 nm blue LED light and biofilm grown on dental surfaces.

· Lasers in Medical Science

Blue LED light with a light-activated agent and dental biofilm — registered clinical trial

Blue light

A registered clinical trial looking at blue LED light used together with a light-activated agent on dental biofilm.

· BMJ Open

Photobiomodulation alongside professional gum care — meta-analysis of 22 studies

Combined / PBM

A meta-analysis pooling 22 clinical studies in which photobiomodulation was used alongside standard professional periodontal care.

· Journal of Biophotonics

Photobiomodulation in periodontal care — systematic review of randomized trials

Combined / PBM

A systematic review of randomized controlled trials in which LED and laser light were used alongside standard professional periodontal care.

· Journal of Periodontology

Low-level laser light in the mouth — systematic review of 14 studies

Combined / PBM

A systematic review covering 14 human and animal studies of low-level laser light in the mouth. The studies used clinical lasers, not LED devices.

· Cureus